Journal of Cytology

: 2010  |  Volume : 27  |  Issue : 3  |  Page : 112-

Burkitts lymphoma of the small intestine: A cytological diagnosis

Ritesh Sachdev 
 Super Religare Laboratories (Formerly, SRL Ranbaxy Pvt. Ltd.), Clinical Reference Lab, Sector-18, Udyog Vihar, Gurgaon, India

Correspondence Address:
Ritesh Sachdev
A 803, Plot 7A, Navrattan Apartments, Sector 23, Dwarka, New Delhi - 110 075

How to cite this article:
Sachdev R. Burkitts lymphoma of the small intestine: A cytological diagnosis.J Cytol 2010;27:112-112

How to cite this URL:
Sachdev R. Burkitts lymphoma of the small intestine: A cytological diagnosis. J Cytol [serial online] 2010 [cited 2021 Jan 22 ];27:112-112
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We describe a case of Burkitt's lymphoma (BL) of the small intestine diagnosed on ultrasound-guided fine needle aspiration cytology (FNAC). BL is a high-grade lymphoma usually involving the mandible and the intestines. An early diagnosis is paramount for prompt and effective management. FNAC forms a rapid and effective tool towards an early detection of these lymphomas. A 5-year-old boy presented with abdominal discomfort and progressively increasing abdominal mass. The computed tomography (CT) scan revealed markedly thickened bowel loops with multiple enlarged lymph nodes. There were well-defined hypoechoic nodular lesions in both the kidneys. A suspicion of lymphomatous origin was raised. Ultrasound-guided FNAC was performed through the thickened bowel. Smears were stained with Giemsa and Papanicolaou stains. Many monomorphic, round to oval single cells were identified. These cells displayed a high nucleo-cytoplasmic ratio, vesicular chromatin and prominent cytoplasmic vacuolization [Figure 1]. Many lymphoglandular bodies were seen scattered in the background. A cytological diagnosis of BL of the small intestine was made. The patient was put on a chemotherapeutic regimen, which resulted in the regression of the abdominal mass.{Figure 1}

The small intestine is a common site of BL in children and is associated with multisystem lesions. Abdominal mass, bone marrow and central nervous system involvement are poor prognostic markers. [1] Total tumor burden is the principal determinant of prognosis. FNAC, along with other ancillary techniques, provides a rapid and simple tool for early diagnosis and treatment. Ogawa et al. [2] used FNAC as a primary tool in the diagnosis of BL of bilateral breasts. Das et al. [3] studied 40 cases of BL and found the intra-abdominal location as a common location in Indian patients. FNAC under guidance can help in a rapid diagnosis, thereby assisting in an early treatment in these high-grade lesions.


The author would sincerely like to thank Dr. Aparna Ahuja, Dr. Simi Bhatia and the Executive Director, Dr. Amar Dasgupta, for their constant support and guidance.


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2Ogawa T, Mizutani M, Yabana T, Miyahara S, Murabayashi K. A case of Burkitt's lymphoma involving both breasts. Breast Cancer 2005;12:234-7.
3Das DK, Gupta SK, Pathak IC, Sharma SC, Datta BN. Burkitt-type lymphoma. Diagnosis by fine needle aspiration cytology. Acta Cytol 1987;31:1-7.