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  Indian J Med Microbiol
 

Figure 2: Smear shows discohesive stromal cells and osteoclastic giant cells (a: Pap stain x100). Stromal cells are pleomorphic with hyperchromatic large irregular nuclei, thick nuclear membrane, clumped chromatin, prominent nucleoli, high N:C ratio, and frquent mitoses (green arrows) (b: Pap stain x400). Sections show pleomorphic stromal cells with frequent mitoses and admixed osteoclastic giant cells (c: H and E stain x100; d: H and E stain x400). Neoplastic stromal cells and osteoclastic giant cells are immunoreactive to CD68 (e: IHC: CD68 x200). Ki67 LI is approximately 40% (f: IHC: Ki67 x200)

Figure 2: Smear shows discohesive stromal cells and osteoclastic giant cells (a: Pap stain x100). Stromal cells are pleomorphic with hyperchromatic large irregular nuclei, thick nuclear membrane, clumped chromatin, prominent nucleoli, high N:C ratio, and frquent mitoses (green arrows) (b: Pap stain x400). Sections show pleomorphic stromal cells with frequent mitoses and admixed osteoclastic giant cells (c: H and E stain x100; d: H and E stain x400). Neoplastic stromal cells and osteoclastic giant cells are immunoreactive to CD68 (e: IHC: CD68 x200). Ki67 LI is approximately 40% (f: IHC: Ki67 x200)