Journal of Cytology
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   2004| October-December  | Volume 21 | Issue 4  
    Online since August 1, 2018

 
 
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ORIGINAL ARTICLES
Fine needle aspiration cytology of lymph nodes - An institutional study of 1448 cases over a five year period
PC Paul, BK Goswami, S Chakrabarti, A Giri, R Pramanik
October-December 2004, 21(4):187-190
Present study is a retrospective analysis of 1448 lymphadenopathy cases, that had undergone FNAC in the Department of Pathology, NBMC for 5 years between 1996 to 2000. Out of total 3964 FNAC performed during the period, FNAC of 330 cases in 1996 increased to 1303 in 2000 indicating higher compliance of the procedure. NBMC is the only referral centre in the region and it reflects the relative occurrence of the disease in the community. This study reveals that tuberculous lymphadenitis (46.34%) is the commonest ailment causing lymphadenopathy followed by metastatic deposits (20.03%) and reactive hyperplasia (18.92%) while lymphoma comprises only 5% cases. Individuals of 16-30 years were most commonly affected by tuberculous lymphadenitis. Cervical group of lymphnodes was the most frequently involved site. Tribal and hilly population, one of the characteristic population group in the region, were found to be the commonest victim of tuberculous lymphadenitis, which may be related to their poor socio-economic status.
[ABSTRACT]   Full text not available  [PDF]
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CASE REPORTS
Medullary carcinoma as a well-circumscribed lesion in the axillary tail of breast: A diagnostic dilemma in fine needle aspiration cytology
DK Das, SK Pathan, RR Makar, R Moosa, MM Iskander, K Mousa
October-December 2004, 21(4):193-196
We report a case of medullary carcinoma of breast in a 48 year old woman, who presented with a 2 x 2 cm mobile lump in the axillary tail of left breast and another mass close to left areola at 7 O'clock position. FNA smear from the axillary tail mass showed pleomorphic malignant cells in clusters and syncytial sheets, amongst rich lympho-plasmacytic cell component. FNA cytology of the mass close to the areola showed features of cystic disease of the breast. Although FNA cytodiagnosis of the mass in the axillary tail was medullary carcinoma (MC), the possibility of a metastatic carcinoma in an intramammary lymph node from an occult primary in the breast could not be ruled out altogether. The patient underwent lumpectomy along with axillary clearance. The lumpectomy specimen confirmed the cytodiagnosis of MC. The neoplastic cells were negative for estrogen and progesterone receptors as well as for cyclin D but positive for c-erb-B 2 and cathepsin D. The patient had an uneventful recovery in the post surgical period. Thus, the diagnosis of medullary carcinoma in axillary tail of breast could be suggested by FNA cytology, which helped the surgeon deciding in favor of lumpectomy but the clinico-cytologic features of this case led to a diagnostic dilemma, necessitating a frozen section confirmation.
[ABSTRACT]   Full text not available  [PDF]
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ORIGINAL ARTICLES
Liposarcoma — Difficulties in FNAC
A Konar
October-December 2004, 21(4):191-192
Eight cases of liposarcoma were studied by FNAC and histopathology. Of these cases, three were pleomorphic liposarcoma, three were spindle cell liposarcoma and two were myxoid liposarcoma. In most of the cases, diagnostic lipoblast was not detected in FNAC, but in histopathology, lipoblast was detected in all cases. In those cases where lipoblast was not detected in FNAC, diagnosis of liposarcoma was not possible by FNAC and these were diagnosed as sarcoma.
[ABSTRACT]   Full text not available  [PDF]
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CASE REPORTS
Recurrent extracranial meningioma with transformation to higher grade (Atypical Meningioma) Diagnosis by cytology
A Sudha, R Power, KVVN Raju
October-December 2004, 21(4):207-210
Meningiomas comprise 13-19% of primary intracranial neoplasms. They may be found extracranialy in sites such as the middle ear, temporal bone, sinonasal cavity, orbit, oral cavity, parotid gland and soft tissue of head and neck. They are called "secondary" if a connection to the CNS is demonstrated. Tumor recurrence may be accompanied by dedifferentiation from a more benign histology and is known to occur in tumors which had gross total resection. Histology, proliferative activity and ploidy studies help in prognostication of natural history of disease, identifying tumors with aggressive behaviour and predicting recurrence, in addition to diagnosis and grading. The case presented here had a benign extracranial meningioma in the left preauricular region with MIB 1 score less than 1 which was excised completely. Recurrence developed at the same site after 1 year and three months associated with atypical cytologic features and extensive intracranial spread. Comparison of FNA pattern in primary and recurrent meningiomas revealed progression of benign meningioma to a higher grade, thereby helping the clinician in effective management.
[ABSTRACT]   Full text not available  [PDF]
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ORIGINAL ARTICLES
Cytology in paediatric malignant solid tumors
AK Das, AK Manna, S Pathak, M Mukhopadhyay, D Guha, A Bhattacharya
October-December 2004, 21(4):171-175
Malignant solid tumors constitute a significant cause of death in paediatric age group. The present study was carried to find out the incidence of various solid malignant tumors in paediatric age groups and for comparative study of fine needle aspiration cytology, imprint cytology and histopathology of these tumors. Out of 30 such cases, we got 9 Wilm's tumors, 7 neuroblastomas, 6 non-Hodgkin's lymphomas (NHL), 5 Ewing's sarcomas, 2 retinoblastomas and 1 rhabdomyosarcoma. Most of the small round cell tumors were found below 5 years of age. There was an overall male predominance. FNAC was done in all 30 cases of which cytological diagnosis was possible in 26 cases. Peroperative imprint cytology was done in 22 cases of which 20 were conclusive. Absolute sensitivity of imprint cytology (0.9) was found slightly better than FNAC (0.86). Histology was done in every case for final conclusion. So FNAC can play a great role for early detection of these malignancies if corroborated with clinicoradiological findings.
[ABSTRACT]   Full text not available  [PDF]
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Fine needle aspiration cytology in granulomatous lesions of skin
N Verma, AK Agarwal, VK Sharma, D Bisht, RP Sharma, M Samat
October-December 2004, 21(4):183-186
This study was undertaken to evaluate the efficacy of aspiration cytology in the diagnosis of granulomatous lesions of the skin. A total of 153 suspected cases were evaluated for detailed cytological features. Histology was available in only 118 cases. Dermal granulomatous lesions are classified as : (1) Predominantly mononuclear (2) Mixed cell and (3) Palisading / Necrobiotic. Among mononuclear group, 151 cases and mixed group 2 cases were reported. Among palisading group, no case was reported. In all the cases cytology correlated well with history. In four cases of leprosy there was no problem in diagnosing leprosy but sub classification on Ridley and Jopling scale differed especially in border line group.
[ABSTRACT]   Full text not available  [PDF]
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Cytology of thyroid lesions with emphasis on non-aspiration technique
S Khan, V Maheshwari, M Aziz, M Husain, AK Verma
October-December 2004, 21(4):179-182
This study was done to compare the diagnostic yield by Non-aspiration technique with fine needle aspiration in thyroid lesions. A significantly higher cell yield was obtained in non-aspiration samples as compared to aspiration samples thus emphasizing the efficacy of this technique over conventional procedure especially in vascular organs like thyroid.
[ABSTRACT]   Full text not available  [PDF]
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CASE REPORTS
Cytologic diagnosis of adenoid cystic carcinoma of parotid
A Santhipriya, A Venkatalakshmi, J Parameswari, PVB Ramalakshmi
October-December 2004, 21(4):205-206
The rare malignant tumor, adenoid cystic carcinoma of parotid has been reported in a 19-year-old male in FNA. The cyto morphological features have been studied. The differential diagnosis are discussed and presented. The study revealed that in such cases fine needle aspiration cytology could be effectively used for cyto diagnosis and in patient management.
[ABSTRACT]   Full text not available  [PDF]
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ORIGINAL ARTICLES
Role of FNAC in metastatic and recurrent osteosarcoma
H Buch, P Trivedi, MJ Shah, SM Patel
October-December 2004, 21(4):176-178
FNA is a simple and safe procedure that is being used for the diagnosis of primary bone tumors. Our study was done with the aim of examining accuracy of this procedure in the diagnosis of recurrent and metastatic osteosarcoma. We found seven patients from our data files that had undergone FNA for disseminated or recurrent osteosarcoma. AH the smears showed pleomorphic spindle cells on the background of pink, homogenous material (osteoid), which varied in proportion in each case. All the cases were diagnosed as osteosarcoma, either recurrent or metastatic. FNA can replace biopsy in follow-up of patients of osteosarcoma.
[ABSTRACT]   Full text not available  [PDF]
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CASE REPORTS
Fine needle aspiration biopsy of endodermal sinus tumor: A case report
JW Mahadani, KS Bharti, SL Khandekar, AV Joshi, MS Walde
October-December 2004, 21(4):199-200
Germ cell tumor comprises 40% of all the testicular neoplasms. FNAB is easy and important method of diagnosis of these tumors. Here we tried to diagnose cytologically endodernial sinus tumor in a 4 year male child. Later the diagnosis was confirmed on histopathological examination.
[ABSTRACT]   Full text not available  [PDF]
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Sialadenosis of parotid gland, Diagnosed by fine needle aspiration — A report of two cases
SPS Arora, MS Bal, P Singal
October-December 2004, 21(4):201-202
Fine Needle Aspiration (FNA) has gained wide acceptance in the evaluation of salivary gland lesions. During the past decade it has been used with high degree of accuracy. Sialadenosis is a bilateral recurrent, non-inflammatory, non-neoplastic disease of salivary glands, mainly the parotids. It is of unknown etiology, mostly associated with an underlying systemic disorder. There is no relation of swelling with meals. Two cases of sialadenosis of parotid gland are being discussed. A 53 year diabetic female presented with a bilateral parotid swelling and the other patient, a 47 year old alcoholic male, presented with bilateral parotid swelling, of six months duration. FNA smears, in both the cases, showed mainly acinar cells with no inflammatory cells.
[ABSTRACT]   Full text not available  [PDF]
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FNAC of myxoid liposarcoma
RGW Pinto
October-December 2004, 21(4):211-213
A rare case of Myxoid Liposarcoma in the upper thigh of a 62 years old man is reported. This case was diagnosed by FNAC and the tumor was excised surgically. The histopathology confirmed the diagnosis of Myxoid Liposarcoma Liposarcomas account for about 20% of all sarcomas in the adulthood, show a slight male predominance and the peak age of onset is the fifth to seventh decade. Myxoid Liposarcoma and its higher grade Round cell type together account for 30-35 % of Liposarcomas. The differential diagnosis to be considered are Myxoma, Myxoid MFH and Round cell Tumors.
[ABSTRACT]   Full text not available  [PDF]
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Sebaceous carcinoma of the eyelid - Cytologic diagnosis

October-December 2004, 21(4):197-198
Carcinomas of sebaceous gland arising from the eyelid have rarely been subjected to fine needle aspiration. We present a case diagnosed on fine needle aspiration cytology in a 65 year old female. A brief review of literature is included.
[ABSTRACT]   Full text not available  [PDF]
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Ganglioneuroma of the posterior mediastinum - A case report
RGW Pinto, S Mandreker, D Lobo, D Amonkar
October-December 2004, 21(4):203-204
Ganglioneuromas are rare tumors and to diagnose ganglioneuromas by FNAC is even rarer. We report a case of ganglioneuroma of the posterior mediastinum in a 7 year old girl which was diagnosed by FNAC, and later on confirmed by histopathology.
[ABSTRACT]   Full text not available  [PDF]
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LETTER TO THE EDITOR
Fine needle aspiration diagnosis of pilomatrixoma
SS Surana, S Bordia
October-December 2004, 21(4):214-214
Full text not available  [PDF]
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