Journal of Cytology
Home About us Ahead of print Instructions Submission Subscribe Advertise Contact e-Alerts Login 
Users Online:242
  Print this page  Email this page Small font sizeDefault font sizeIncrease font size
CASE REPORT
Year : 2017  |  Volume : 34  |  Issue : 1  |  Page : 63-65

Intraoperative squash cytology and histology of giant cell ependymoma: A diagnostic dilemma


1 Department of Pathology, Izmir Tepecik Education and Research Hospital, Izmir, Turkey
2 Department of Pathology, Faculty of Medicine, Dokuz Eylul University, Izmir, Turkey
3 Department of Neurosurgery, Izmir Tepecik Education and Research Hospital, Izmir, Turkey

Correspondence Address:
Ebru Cakir
Department of Pathology, Izmir Tepecik Education and Research Hospital, Yenisehir, Izmir
Turkey
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0970-9371.197625

Rights and Permissions

Giant cell ependymomas (GCE) are extremely rare tumors, with 24 cases described in the literature. Squash cytology is a rapid, reliable, simple technique for intraoperative consultation in neurosurgical practice. We describe a rare case of GCE arising at level of L4-L5 in a 66-year-old woman and discuss the cytologic/histologic features. Intraoperative smears were highly cellular with a prominent fibrillary background and exhibited papillary structures and sheets composed of highly atypical and bizarre cells. Some of the cells showed nuclear pseudoinclusions and rarely formed pseudorosette-like arrays. Intraoperative diagnosis was high grade glial tumor. On paraffin sections, besides extensive polymorphism, there were no microvascular proliferation, necrosis, and mitosis and the final diagnosis was WHO grade II GCE. GCE may be a diagnostic challenge on intraoperative smears, frozen, and paraffin sections. It must be kept in mind in the differential diagnosis of giant cell exhibiting benign and malignant tumors of brain.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed517    
    Printed3    
    Emailed0    
    PDF Downloaded25    
    Comments [Add]    

Recommend this journal