Journal of Cytology
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CASE REPORT
Year : 2017  |  Volume : 34  |  Issue : 1  |  Page : 45-48

Penicillium marneffei infection in a HIV-Positive patient: A comparison of bronchial washing cytology and biopsy


Department of Pathology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea

Correspondence Address:
Kyung Ja Cho
Department of Pathology, University of Ulsan College of Medicine, Asan Medical Center, Seoul - 138-736
Korea
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0970-9371.197618

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Penicilliosis is a disseminated and progressive infection that is mainly found in immunocompromised individuals, especially those with human immunodeficiency virus (HIV) infection. Because of the high mortality of patients with disseminated Penicillium marneffei infection, rapid diagnosis and early treatment are required. Diagnosis is traditionally made by biopsy and/or culture of blood or any involved organ. Cytology offers several advantages over biopsy, including more rapid diagnosis and greater resolution of cytomorphologic details of organisms, allowing rapid initiation of treatment. Here, we describe a case of penicilliosis in an HIV-positive patient with emphasis on the morphological characteristics of the organism in cytologic specimens, as well as a comparison of bronchial washing and biopsy findings.


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