Journal of Cytology
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CASE REPORT
Year : 2016  |  Volume : 33  |  Issue : 4  |  Page : 232-235

Kimura's disease: A diagnostic challenge experienced with cytology of postauricular swelling with histopathological relevance


Department of Pathology, Sikkim Manipal Institute of Medical Sciences, Gangtok, Sikkim, India

Correspondence Address:
Dr. Mingma Sherpa
Department of Pathology, Sikkim Manipal Institute of Medical Sciences, Gangtok - 737 101, Sikkim
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0970-9371.190453

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Kimura's disease is a rare, chronic inflammatory disorder of unknown cause. It is endemic in Asia, affecting more number of males than females, with a ratio of 3:1. The typical clinical manifestations include a triad of painless unilateral cervical lymphadenopathy or subcutaneous masses predominantly in the head and neck region, blood and tissue eosinophilia, and an elevated serum immunoglobulin E (IgE) levels. Variable conditions both benign and malignant may mimic Kimura's disease both clinically and on fine needle aspirates. The confirmatory diagnosis is established only by histopathological examination. We report a case of Kimura's disease in a patient who underwent multiple investigations in view of her past history and family history of pulmonary Koch's. Fine needle aspiration cytology (FNAC) was performed thrice with consistently similar result of reactive lymphadenitis with numerous histiocytes and eosinophilia. The final diagnosis of Kimura's disease could finally be established only on histopathological examination.


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