Journal of Cytology
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CASE REPORT
Year : 2014  |  Volume : 31  |  Issue : 4  |  Page : 218-220

Primary thyroid lymphoma: A rare disease


Department of Pathology, Lady Hardinge Medical College and Shrimati Sucheta Kriplani Hospital, New Delhi, India

Correspondence Address:
Deepti Verma
Department of Pathology, Lady Hardinge Medical College and Shrimati Sucheta Kriplani Hospital, Shaheed Bhagat Singh Marg, New Delhi
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0970-9371.151139

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Primary thyroid lymphomas are rare neoplasms comprising of 1-5% of thyroid malignancies. These are predominantly B-cell in origin. Here, we report a case of 60 years lady, a known case of lymphocytic thyroiditis, diagnosed as thyroid lymphoma (diffuse large B-cell) on fine needle aspiration and confirmed histopathogically and immunohistochemically. She presented with a sudden increase in thyroid swelling. Fine needle aspiration performed showed highly cellular smears comprising predominantly of the monomorphic population of medium to large sized lymphoid cells with high nuclear/cytoplasmic ratio and scant cytoplasm. A possibility of thyroid lymphoma possibly diffuse large B-cell lymphoma was suggested which was later confirmed on biopsy. Fine needle aspiration provides an easy mode for diagnosing large cell lymphoma like diffuse large B-cell. Hence, an early diagnosis is possible for a timely intervention. Also, cases of lymphocytic thyroiditis should be regularly followed for the development of lymphoma.


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