Journal of Cytology
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Year : 2014  |  Volume : 31  |  Issue : 4  |  Page : 183-188

Integrated cervical smear screening using liquid based cytology and bioimpedance analysis

1 School of Medical Science and Technology, Indian Institute of Technology Kharagpur, Kharagpur, India
2 Department of Radiology, Apollo Gleanengles Hospital, Midnapore, India
3 Department of Pathology, Midnapore Medical College and Hospital, Midnapore, India
4 Department of Pathology, Calcutta National Medical College, Kolkata, West Bengal, India

Correspondence Address:
Lopamudra Das
School of Medical Science and Technology, Indian Institute of Technology Kharagpur, Kharagpur - 721 302, Kolkata, West Bengal
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Source of Support: Department of Information Technology (DIT), Govt. of India, New Delhi, Conflict of Interest: None

DOI: 10.4103/0970-9371.151127

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Objective: To minimize the false negativity in cervical cancer screening with Papanicolaou (Pap) test, there is a need to explore novel cytological technique and identification of unique and important cellular features from the perspectives of morphological as well as biophysical properties. Materials and Methods: The present study explores the feasibility of low-cost cervical monolayer techniques in extracting cyto-pathological features to classify normal and abnormal conditions. The cervical cells were also analyzed in respect to their electrical bioimpedance. Result: The results show that newly developed monolayer technique for cervical smears is cost effective, capable of cyto-pathological evaluation. Electrical bioimpedance study evidenced distinction between abnormal and normal cell population at more than two order of magnitude difference. Conclusion: The integration of bioimpedance observation along with the proposed low-cost monolayer technology could increase the efficiency of the cervical screening to a greater extent thereby reducing the rates of faulty diagnosis.

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