Journal of Cytology
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CASE REPORT
Year : 2014  |  Volume : 31  |  Issue : 1  |  Page : 36-39

Lipomatous pleomorphic adenoma in the hard palate: Report of a rare case with cyto-histo correlation and review


1 Department of Pathology, Azerbaijan Medical University, Baku, Azerbaijan
2 Department of Pathology and Cytology, Ankara Diskapi Teaching and Research Hospital, Ankara 06110, Turkey
3 Department of Oral and Maxillofacial Surgery, Azerbaijan Medical University, Baku, Azerbaijan

Correspondence Address:
Jamal Musayev
Department of Pathology, Azerbaijan Medical University, Baku, Republic of Azerbaijan. Patoloji Anatomiya Burosu, Sherifzade 212, AZ1012, Baku
Azerbaijan
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0970-9371.130689

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Pleomorphic adenoma is the most common benign tumor of the salivary glands. They are usually composed of epithelial/myoepithelial cells and chondromyxoid stroma. Extensive lipomatous differentiation is very rare. We report a case of lipomatous pleomorphic adenoma (LPA) that presented with a mass in the hard palate of a 32-year-old woman. The fine-needle aspiration cytology material was reported as benign cytology consistent with adenoma with major adipocytic component. Histopathological examination of the excision material displayed that more than 90% of the tumor was adipocytic in texture, containing scant epithelial and myoepithelial cells and chondromyxoid stromal fragments. Preoperative cytodiagnosis of lipomatous pleomorphic adenoma on FNA is based on cytomorphology intimately associated pleomorphic adenomatous and lipomatous tissue elements. LPA should be on the mental list of the (cyto)pathologist in differential diagnosis of lipomatous tumors or non-tumorous lipomatosis or carcinoma invasion in the adipose tissue of the minor salivary gland of the hard palate.


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