Journal of Cytology
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Year : 2012  |  Volume : 29  |  Issue : 1  |  Page : 80-82

Oncocytic lesion of parotid gland: A dilemma for cytopathologists

1 Department of Pathology, North Bengal Medical College, Darjeeling, India
2 Consultant Pathologist, Department of Pathology, Jalpaiguri District Hospital, West Bengal, India
3 Department of Community Medicine, North Bengal Medical College, Darjeeling, India

Correspondence Address:
Indranil Chakrabarti
Department of Pathology, North Bengal Medical College, Sushrutanagar, District Darjeeling, West Bengal 734 012
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0970-9371.93236

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Oncocytes are epithelial cells with abundant, granular, eosinophilic cytoplasm due to presence of numerous large mitochondria of varied sizes. The presence of oncocytes in salivary glands can occur in a variety of conditions. Here, we present a rare case of a 68 year old male patient who presented with a 6 cm diameter swelling in the right parotid region. A fine needle aspiration cytology done from the lesion showed a cellular oncocytic lesion. A possibility of oncocytoma was entertained. Histopathology of the mass showed a rare entity called diffuse hyperplastic oncocytosis. Originally believed to be a metaplastic process, oncocytes can occur in various lesions ranging from hyperplastic conditions to malignant neoplasms. However, diagnosis on cytological smears can be very challenging for the cytopathologist.

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