Journal of Cytology
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Year : 2011  |  Volume : 28  |  Issue : 2  |  Page : 77-80

Imprint cytology of the chromophobe renal cell carcinoma: Correlation with the histological and ultrastructural features

Department of Pathology, Dankook University College of Medicine, Cheonan, Korea

Correspondence Address:
Wonae Lee
Department of Pathology, Dankook University College of Medicine, 16-5 Anseo-Dong, Cheonan Chungcheong Nam Do, 330-715, Korea
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Source of Support: Dankook University in 2009, Conflict of Interest: None

DOI: 10.4103/0970-9371.80749

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Chromophobe renal cell carcinoma (ChRCC) is a unique entity of renal cell carcinoma and has a low malignant potential. A correct cytological diagnosis can help to decide the suitable management and operation. I present here a case with an imprint cytology of ChRCC focusing on the correlation with the histological and ultrastructural features. A 69-year-old male underwent partial nephrectomy and imprint cytology. The cellular smear consisted of predominantly granular eosinophilic cells with round nuclei, a well-defined cytoplasmic membrane and accentuated cell borders. The cytoplasm was characterized by variable granularity with reticulated clearing or vague perinuclear vacuolization. Distinct perinuclear halos were infrequently noted. The histological, immunohistochemical and ultrastructural findings were compatible with ChRCC.

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