Journal of Cytology
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ORIGINAL ARTICLE
Year : 2006  |  Volume : 23  |  Issue : 3  |  Page : 133-137

Evaluation of malignant liver neoplasms by fine needle aspiration cytology


1 Professor and Head, Pathology; Jawahar Lai Nehru Medical College, Ajmer, Rajasthan, India
2 Senior Demonstrator, Pathology; Jawahar Lai Nehru Medical College, Ajmer, Rajasthan, India
3 Assistant Professor Medicine, Pathology; Jawahar Lai Nehru Medical College, Ajmer, Rajasthan, India
4 Assistant Professor, Pathology; Jawahar Lai Nehru Medical College, Ajmer, Rajasthan, India

Correspondence Address:
N Prasad
G-138, Makarwali Road, Vaishali Nagar, Ajmer, Rajasthan
India
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Source of Support: None, Conflict of Interest: None


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Fine needle aspiration cytology (FNAC) of 298 neoplastic lesions with and without ultrasonography guidance is presented. The study covers a period of 21 years from 1984-2005. Biopsy of liver and other involved secondary sites was available in 211 cases. In the remaining cases, similarity of the morphologic features of aspiration smears to those of histologically confirmed cases gave a reasonable certainty of diagnosis. Adequacy of fine needle aspirates was found to be better than trucut needle biopsy where adequacy of material was only 80%. There were 115 hepatocellular carcinoma, 174 metastatic tumours, 3 hepatoblastomas 1 cholangiocarcinoma and 5 unspecified malignancies. The false negative rate was 10.43%. There was no false positivity. The sensitivity was 90% and specificity 100%. FNAC was found to be a safe, cost effective accurate procedure which could be repeated without any complications.


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