Journal of Cytology
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ORIGINAL ARTICLE
Year : 2006  |  Volume : 23  |  Issue : 1  |  Page : 7-9

The utility of cytology in the diagnosis of Gardnerella Vaginalis infection


1 Professor, Department of Pathology, JNMC, AMU, Aligarh, India
2 Professor, Department of Microbiology, JNMC, AMU, Aligarh, India
3 Professor, Department of Obstetrics & Gynaecology, JNMC, AMU, Aligarh, India
4 Resident, Department of Obstetrics & Gynaecology, JNMC, AMU, Aligarh, India
5 Senior Resident, Department of Pathology, JNMC, AMU, Aligarh, India
6 Junior Resident, Department of Pathology, JNMC, AMU, Aligarh, India

Correspondence Address:
L Khan
Department of Pathology, A.M.U., Aligarh, Uttar Pradesh 202 002
India
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Source of Support: None, Conflict of Interest: None


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Gardnerella vaginalis has been often implicated as the commonest causative organism of bacterial vaginosis. We studied 88 cases of bacterial vaginosis to establish the role of G. Vaginalis in its causation and to study the role of clue cells in the diagnosis of G. Vaginalis infection. Various criteria like presence of characteristic vaginal discharge, pH > 4.5, positive amine test (PAT), gram’s stain for clue cells and culture were applied to these cases for detection of G. Vaginalis. On studying the value of different test against positive culture we found that the criteria of clue cells have good sensitivity (48.3%), high specificity (98.2%) and remarkably high predictive value (93.7%). The predictive value was quite low in case of characteristic discharge (42.0%), pH > 4.5 (59.3%) and PAT (58.3%). Detection of clue cells is an easy and quick method and together with any other one or two criteria it is reliable for detection of G. Vaginalis in cases of bacterial vaginosis as culture is negative in large number of cases.


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