Journal of Cytology
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ORIGINAL ARTICLE
Year : 2006  |  Volume : 23  |  Issue : 1  |  Page : 11-17

Utility of fine needle aspiration cytology in evaluating mediastinal masses


1 Reader, Department of Pathology, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh 202 002, India
2 Senior Resident, Department of Pathology, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh 202 002, India
3 Lecturer, Department of Pathology, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh 202 002, India
4 Professor, TB & Chest, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh 202 002, India
5 Lecturer, Department of Pathology, Radiodiagnosis, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh 202 002, India

Correspondence Address:
R Sherwani
Reader, Department of Pathology, JNMC, AMU, Aligarh, Uttarpradesh 202 002
India
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Source of Support: None, Conflict of Interest: None


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The aim of the current work is to perform a comprehensive study of medistinal mass and assess the utility of fine needle aspiration in diagnosing various mediastinal lesions. The study was conducted on 56 patients presenting with a mediastinal mass on chest radiograph or on computed tomography scan. Males were predominantly affected, 48 cases (85.7%) and presented mainly in the 6th decade. Majority of the lesions (30%) were located in the anterosuperior mediastinum. 12 cases (21.4%) were diagnosed as benign and 36 cases (64.3%) as malignant where carcinoma formed the single largest category, 28 cases. Metastatic disease represented the single largest category of lesions on FNA cytology of mediastinum (28 cases) with minimum number of cases 23 (82.0%) originating from a lung primary. A concordant cytohistopathological correlation was obtained in 19 out of the 20 cases studied. Sensitivity and specificity of FNAC of mediastinal masses was found out to be 97% and 700% respectively with 100% diagnostic accuracy of malignant lesions and 91.6% for benign lesions.


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