Journal of Cytology
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ORIGINAL ARTICLE
Year : 2004  |  Volume : 21  |  Issue : 3  |  Page : 140-143

Fine needle aspiration cytology of parathyroid neoplasms


1 Assistant Professor, Department of Histopathology, Postgraduate Institute of Medical Education and Research, Chandigarh - 160 012, India
2 Assistant Professor, Department of Immunopathology, Postgraduate Institute of Medical Education and Research, Chandigarh - 160 012, India
3 Associate Professor, Postgraduate Institute of Medical Education and Research, Chandigarh - 160 012, India
4 Professor and Head, Department of Cytology and Gynecological Pathology, Postgraduate Institute of Medical Education and Research, Chandigarh - 160 012, India

Correspondence Address:
U N Saikia
Assistant Professor, Department of Histopathology, PGIMER, Chandigarh - 160 012
India
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Source of Support: None, Conflict of Interest: None


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A total of five cases of parathyroid neoplasm including four of parathyroid adenoma (PA) and one case of parathyroid carcinoma (PC) with available cytology and histology were studied. The salient cytological features included predominant dissociated epithelial cells with small groups palisading around capillaries, more so in PC. Minimal nuclear pleomorphism with evenly dispersed nuclear chromatin and presence of single to multiple inconspicuous nucleoli differentiate parathyroid from thyroid neoplasms. Presence of abundant pale blue cytoplasm showing vacuolations and lipophages in the background are soft pointers to neoplasm of parathyroid in origin. Cytology together with the clinical, biochemical, and radiological data may allow the recognition of parathyroid neoplasms prior to surgical intervention.


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