Journal of Cytology
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ORIGINAL ARTICLE
Year : 1997  |  Volume : 14  |  Issue : 2  |  Page : 21-26

Utility of fine needle aspiration cytology in orbital tumours


1 Professor, Department of Pathology, K.G. Medical College, Lucknow, India
2 Research Assistant, Department of Pathology, K.G. Medical College, Lucknow, India
3 Resident, Department of Pathology, K.G. Medical College, Lucknow, India
4 Associate Professor, Department of Pathology, K.G. Medical College, Lucknow, India

Correspondence Address:
M M Goel
Associate Professor, Dept. of Pathology, KG MedicalCollege, Lucknow -226003
India
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Source of Support: None, Conflict of Interest: None


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Cytohistopathological correlation and assessment of diagnostic accuracy of FNAC was possible in 49 of 91 cytodiagnosed orbital masses. It showed 80% sensitivity, 72.4% specificity, 95.5% Positive Predictive Value (PPV) and Negative Predictive Value (NPV) of only 33.3%. On thorough review of false positive and all negative cases reported earlier, the false negatives were reduced to only two hence increasing the NPV from 33.3 to 66.7%, sensitivity from 72.4 to 91.3% and efficiency from 73.5 to 86.2%. Both sampling error and the method of interpretation in cytologic reporting affect the diagnostic indices. While the false positive reports affect the PPV, false negative reporting is equally important as it reduces the NPV. Therefore all negative and false positive reports should be critically reviewed along with individual follow up of all the cases to ensure a better quality assurance in diagnostic cytology.


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