Journal of Cytology
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CASE REPORTS
Year : 1995  |  Volume : 12  |  Issue : 1  |  Page : 48-51

Malignant melanoma presenting as chronic menignitis-cytological diagnosis of cerebrospinal fluid -- A case report


1 Department of Neurology, National Institute of Mental Health and Neurosciences Bangalore - 560 029, India
2 Department of Microbiology, National Institute of Mental Health and Neurosciences Bangalore - 560 029, India
3 Department of Pathology, National Institute of Mental Health and Neurosciences Bangalore - 560 029, India

Correspondence Address:
S K Shankar
Additional Professor, Dept. of Neuropathology, NIMHANS, Bangalore-560 029
India
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Source of Support: None, Conflict of Interest: None


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The sole presentation of a malignant melanoma as carcinomatous meningitises extremely fare. Herein, we report a 17year old patient presenting with features of meningitis who had melanoma cells in the CSF. This patient was initially diagnosed as tuberculous meningitis but a lack of response to specific antituberculous therapy led us to investigate for other causes of meningitis. Repeated examination of the lumbar CSF for malignant cells by cytospin preparation showed abnormal cells containing dark brown pigment. As this pigment could be bleached it was considered to be melanin and not haemosiderin confirming the abnormal cells to be from a melanoma. There was no evidence of a melanoma elsewhere in the body in our patient.


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